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Not everyone benefits from split dosing, and single morning administration works well for many users

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For research purposes only

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The evidence has been largely RNA- and protein-based with increased concentrations of interleukin (IL)-4, tumor necrosis factor (TNF)- , soluble TNF receptor 1 (sTNFR1), and soluble IL-2 receptor consistently reported in BD compared to healthy controls [67, 68]