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Active cancer or history of malignancy Pregnancy or breastfeeding Known peptide allergies Athletes subject to anti-doping testing (WADA prohibited) Raynauds disease or phenomenon Cold urticaria (hives from cold) Uncontrolled hypertension Peripheral vascular disease Open wounds (for local application) Pregnancy Cardiovascular conditions Diabetes (especially with neuropathy) Current infections Immunosuppression Blood clotting disorders Quality control issues represent perhaps the greatest practical risk with BPC-157

UCSF ChimeraX: tools for structure building and analysis

The peptide also increases elastin production by 30% and dramatically upregulates decorin, a proteoglycan that regulates collagen organization

doi:10.1155/2015/648108 Philp D, Goldstein AL, Kleinman HK

"Peptide therapy with pentadecapeptide BPC 157 in traumatic nerve injury." Regulatory Peptides, 2010

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