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In practice, this combination would need to be evaluated by a supervising physician with careful monitoring

It is primarily involved in the transport of long-chain fatty acids into the mitochondria of cells, where they are oxidized to produce energy

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The reasons for these changes, apart from excess ROS leading to increased GSH depletion in cardiomyocytes, are disturbances in the anabolic process of GSH, causing a further decrease in intracellular GSH content