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This updated guidance states that most patients should continue taking their glucagon-like peptide-1 receptor agonists before elective surgery with emphasis on individualised risk assessment and shared decision-making [41]
In this sense, they may be thought of as disease-modifying agents instead of glucose-lowering therapy
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Recent neuroimaging studies have shown that obesity is associated with measurable changes in brain anatomy, including reductions in gray matter volume in regions involved in executive function, memory, and decision-making
Metabolic adaptation compounds the problem
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