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First, it hits GLP-1 receptors, the same ones targeted by semaglutide and tirzepatide, helping regulate appetite and food intake

A triple receptor agonist peptide targeting GLP-1, GIP, and glucagon pathways, studied for multi-receptor signaling mechanisms and metabolic pathway interactions in controlled laboratory settings

Discovery of a novel series of orally bioavailable and CNS penetrant Glucagon-Like Peptide 1 Receptor (GLP-1R) non-competitive antagonists based on a 1,3-disubstituted-7-aryl-5,5-bis(trifluoromethyl)-5,8-dihydropyrimido[4,5-d]pyrimidine-2,4(1H,3H)-dione core

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