Collectively, these findings demonstrate that psychological trauma initiates a cascade of interconnected MGBA disruptions in PTSD, encompassing HPA axis dysregulation, microbial dysbiosis, compromised gut barrier integrity, chronic inflammation and neurotransmitter imbalances across serotonergic, dopaminergic, and GABAergic systems
Barhwal K, Hota SK, Prasad D, Singh SB, Ilavazhagan G
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Understanding these cardiovascular effects is essential for safe prescribing and monitoring, particularly in patients with baseline hypotension or those taking antihypertensive medications
TRIUMPH-1 (NCT05929066) will look at the efficacy and safety of retatrutide in people with overweight/obesity without T2D and will include subsets of participants with knee osteoarthritis (OA) or OSA
[2] Gatti, G., Barzaghi, N., Acuto, G., Abbiati, G., Fossati, T., & Perucca, E