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The data were, however, not compatible with a protective intention-to-treat effect. They concluded: Randomized trials using MALO as an outcome might be unfeasible, motivating further large observational studies using appropriate methodology to further delineate the effect of GLP1 agonists on the risk of MALO, complementing future phase 3 trials of GLP1 agonists.
Elsevier Science Publishers BV, Amsterdam, pp 106159 Cengiz M, lker P, ykl M et al (2016) Effect of magnesium supplementation on blood rheology in NOS inhibition-induced hypertension model
The authors point to the systemic effects of these medications as one possible explanation for the findings
However, thanks to TikTok influencers and celebrity use, many people without diabetes are now asking their doctors to prescribe these drugs to help them lose weight
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