It does not play well with strong actives that drive exfoliation or shift skin pH
Some researchers eventually use up to 100mg daily for enhanced effects, though this should be approached gradually
In research models, inhibiting NNMT has been associated with preserved SAM and NAD availability, which is the mechanistic basis for studies into cellular energy and substrate handling
The exact number of B12 injections that you will need to have, and their frequency, will be determined by the extent of the impact that your deficiency has on your health
Presented for research literature review only Cole LA (2009)
Symptoms of real deficiency include fatigue, tingling or numbness in hands and feet, memory and concentration issues, mouth ulcers and pale skin, and a GP blood test is the only reliable way to confirm it