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Unlike other GH secretagogues, ipamorelin very surprisingly does not induce a significant increase in adrenocorticotropic hormone (ACTH) or cortisol
Clinical trials of sermorelin did not include patients with pituitary tumors or other brain lesions causing hormone deficiencies, so safety and efficacy in this group are not established
Brief Background Bacteriostatic formulations were adopted widely in the mid-20th century to address contamination risks when a sterile container is accessed more than once
Research-grade peptides carry higher risks from impurities and inconsistent dosing
Five very important hormones/enzymes are produced by the kidney, viz, 1,25-dihydroxyvitamin D3, erythropoietin, renin, Klotho, and kallikrein (Haussler et al