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Cells were plated in collagen-coated 96-well plates at the density of 2 10 4 per well in 0.1 mL DMEM
The dual benefit makes it particularly valuable for the large overlap population of people who are both overweight and insulin resistant
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However, even in large real world cohorts of patients with T1D on GLP-1RA, low rates of hypoglycemia were observed ( ADJUNCT ONE and TWO trials, the 2 largest studies with GLP-1RA in T1D, reported increased rates of hypoglycemia
