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Maintenance dose: 0.6 to 1.8 mg subcutaneously 1 time a day

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86% of participants Achieved an A1c less than 7% Lost up to 11.2 kg (24.64 lbs) Trial #3 Compared tirzepatide with patients on metformin with/without SGLT-2 to degludec

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Western blot analysis Western blotting was performed as previously described via the following antibodies: FBXO22, BACH1, KLF4, LKB1, SNAL1, PTEN, KDM4A, BAG3, and GAPDH (all from Proteintech, Rosemout, IL)

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