Mol Endocrinol (Baltimore Md.)
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Activated caspase-8 can either directly cleave and activate executioner caspases, or in many beta cells, cleave the BH3-only protein Bid to produce tBid, which is transported to the mitochondria and potentiates the intrinsic pathway, a kind of crosstalk [99]
They also discussed what this means for the future of health, food and nutrition
Progress on the function and application of thymosin 4