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Researchers use in-vitro models of pulmonary fibrosis to study this process, often by treating lung fibroblast cell lines (e.g., MRC-5) with the pro-fibrotic cytokine TGF-1
In real-world tolerance tests, a repeat-insult patch test on an eye lotion with 0.2% Centella extract showed no irritation or allergic contact dermatitis in 54 subjects
The GLP-1-induced hyperpolarization is accompanied by an increase in membrane conductance suggesting the opening of potassium channels (Williams et al., 2018)
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