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When you inject in the same spot repeatedly, that tissue can thicken and become less responsive to medication, a condition called lipohypertrophy

Studies in tendon fibroblasts show that BPC-157 dose-dependently and time-dependently increases growth hormone receptor expression at both mRNA and protein levels

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This corresponds to the general evidence that BPC 157 was used in ulcerative colitis trial and duodenal lesions counteraction