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The inert chemistry of the MSIA tips provide reduced nonspecific binding, lowering background and minimizing the work load on LC systems, which contribute to increased signal-to-noise and improved assay sensitivity, as shown in Figure 2
Examples of approaches include conjugation to peptide carriers (e.g., to polylactic-co-glycolic acid [PLGA])
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[64] Initially in high daily doses, followed by less frequent lower doses, as the condition improves
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