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doi: 10.1074/jbc.M805287200 89 ChenKKirberMTXiaoHYangYKeaneyJFJr.Regulation of ROS signal transduction by NADPH oxidase 4 localization

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doi:10.1185/030079908X280707

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PubMed CrossRef Kahn SE, Haffner SM, Heise MA, et al

While some studies found no difference between individuals with T2DM and matched non-diabetic controls (6769), others found plasma DPP-4 activity to be reduced in the patients, and suggested this might reflect a compensatory response to the reduced insulin sensitivity and hyperglycaemia, in an attempt to increase intact incretin hormone concentrations and improve insulin secretion (70, 71)