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remission: When the provider documents Crohns disease in remission, assign the appropriate K50.x0 code (without complications, e.g., K50.00, K50.10, K50.80, K50.90)

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Reduced calorie diet combined with NNMT inhibition establishes a distinct microbiome in DIO mice. Scientific Reports (2022): 484

Mechanistically, NNMT suppression increased adipose SAM and NAD, upregulated polyamine flux enzymes (ODC, SSAT), and altered histone methylation consistent with a shift toward oxidative metabolism [2]

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Remember that clinical trials failed to demonstrate statistically significant weight loss in the largest study, leading to development termination in 2007