26 Certain GLP-1 agonist drugs have been associated with a significantly increased risk of depression and anxiety, 27 highlighting an emerging need for complimentary therapies to support patients mental and emotional health while undergoing pharmaceutical GLP-1 therapy
Notable exclusions include antibodies, label expansion, biosimilars
Early trial results In phase 2 trials, Retatrutide delivered impressive results: Mean weight reduction of up to ~17.5% at 24 weeks, rising to ~24.2% at 48 weeks in overweight/obese adults
Methods This was a substudy of a randomised clinical trial on the effects of semaglutide and empagliflozin alone or in combination
Gilkerson RW, De Vries RL, Lebot P, Wikstrom JD, Torgyekes E, Shirihai OS, et al
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