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The medication continues to improve insulin sensitivity, which can protect against the risk of developing diabetes or heart disease in the long run

Tirzepatide is a breakthrough medication that has gained attention for its remarkable impact on weight loss

Intermediate effect sizes are considered biologically meaningful because average proportions of variance explained in physiological, ecological and evolutionary studies are usually below 7% 32

PMC 3005101

This occurs because semaglutide slows gastric emptying as part of its mechanism of action, which can lead to harder, less frequent stools

So that tells me that, since it's a very small minority that are coming off for side effects, most people are having them ripped away from them by political and financial reasons