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For example, the known protein phosphatase protein tyrosine phosphatase B (PtpB) from Mycobacterium tuberculosis dephosphorylates phosphatidylinositol-4-phosphate and phosphatidylinositol-(4,5)-bisphosphate in host cell membranes, which disrupts the membrane localization of cleaved gasdermin D (GSDMD), thereby inhibiting cytokine release and pyroptosis in macrophages

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All values are expressed as mean standard deviation

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