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The proposed mechanisms include activation of the hypothalamicpituitaryadrenal (HPA) axis and the sympathetic nervous system, leading to altered cytokine profiles and immune dysregulation
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Limberg JK, Kellawan JM, Harrell JW et al (2014) Cardiovascular consequences of obesity and type 2 diabetes: exercise-mediated vasodilation in human obesity and metabolic syndrome: effect of acute ascorbic acid infusion
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10.1161/CIRCIMAGING.109.899377 7