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These hormones play a significant role in metabolic health
Endocrinology 157 , 16601672 (2016)
Thus, initial insurance hurdles may be resolved with the first or second agent, whereas clinical factors take precedence in driving further therapy changes
Eric Topol, in a July 2025 review of the evidence on peptide therapies, grouped ipamorelin with CJC-1295 and tesamorelin as growth-hormone-related peptides that "carry the potential risk of cancer" on mechanistic grounds, because sustained IGF-1 elevation promotes cell proliferation broadly [4]
9 : 3946 Taglialatela G, Angelucci L, Ramacci MT, Werrbach-Perez K, Jackson GR, Perez-Polo JR
They are not prescribed specifically for perimenopause but may help address metabolic complications associated with this life stage
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