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After a median follow-up of two years and a maximum of three years, cardiovascular death or worsening heart failure events occurred in 9.9% of the tirzepatide group and 15.3% of those taking placebo
Published data from the Phase 3b STRIDE trial reported that Ozempic 1 mg via SC injection once weekly improved maximum walking distance by 13% relative to placebo after 52 weeks
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When such drugs are administered to a patient receiving Janumet the patient should be closely observed to maintain adequate glycemic control
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If a meaningful portion of retatrutide weight loss comes from increased metabolic rate rather than purely reduced intake, the nutritional stress on follicles may be somewhat less severe than the raw weight loss numbers would predict
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