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But when I hear clinicians talk about this and who the kinds of conversations they have with patients it sort of comes back to that earlier conversation we had where I'll hear the phrase a lot: you know, they've got this BMI or this obesity and they've tried everything else and it hasn't worked and now we're going to talk about the pharmaceutical

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Semaglutide is primarily eliminated via proteolytic degradation rather than renal excretion, meaning that no dose adjustment is required for patients with mild, moderate or severe renal impairment