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Mitochondrial metabolism and ROS generation are essential for Kras-mediated tumorigenicity
However, when intracellular iron ions are overloaded, Fe 2+ can catalyze the generation of metabolically toxic reactive oxygen species and phospholipid peroxide through the Fenton reaction, leading to cell damage or death (Ingold et al., 2018) (Figure 4)
It should be used exclusively by qualified researchers and professionals for experimental studies
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ii) Utilizing the steric hindrance conferred by dimerization reduces protease access to the active site and significantly improving stability against proteases 49,50
Thus, this peptide can increase and accelerate blood flow in the area of injuries, which is normally very slow, it is very efficient in enhancing healing processes
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