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The problem is that impurities from the recombinant process are not always the same from batch to batch and can be toxic and hard to remove
The most clinically documented interaction is with cyclosporine, where berberine can significantly increase blood levels, potentially requiring dose adjustments and therapeutic drug monitoring
Availability of analytical documentation will be indicated on the product listing or supplied where applicable
Some patients find that bland foods such as toast, crackers, or rice are better tolerated when nausea is prominent
Exposure to high humidity can lead to several detrimental effects: Clumping or caking of the powder Reduced stability and potency Potential microbial growth Difficulties in reconstitution To combat these issues, manufacturers employ various strategies
Precision nutrition and the microbiome, part I: current state of the science
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