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What we think of as one thing, vitamin B12, is actually more of a category of very similar molecules, known as cobalamin
The clinical implications of this framework are profound
And, given the individual variability, Dr
95% confidence interval: 0.74;1.15, not statistically significant over the length of the trial)
The fourth tissue slide was used for visualization of T-lymphocytes, by using an antibody directed against CD3 (Abcam, dilution 1:100)
The MDS-UPDRS and CDR-SB cannot cleanly separate symptomatic relief from disease modification, and EVOKE showed the converse failure mode, biomarker movement without clinical benefit, so future trials should anchor on objective measures such as dopamine-transporter SPECT, neurofilament light chain, and tau, amyloid, and neuroinflammation PET
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