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While rodents exhibit depression-like behaviors (e.g., anhedonia in sucrose preference tests) after chronic ethanol exposure, human depression is a multifaceted construct encompassing emotional, cognitive, and somatic symptoms (Olney et al

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P-T (placebo to tesamorelin) refers to the group of patients who received placebo for Weeks 0-26 and were switched to tesamorelin (treated open label) for Weeks 26-52