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These are large effect sizes for a condition where neurology has historically had few effective interventions

This long duration is a benefit for weekly dosing, as it keeps the medication stable in your system

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Oral B12 supplements are non-invasive and convenient but may have lower absorption rates

The hypoglycemia stimulates glucagon release from the pancreas and epinephrine release from the adrenal glands leading to increased fatty acid release from adipose tissue

Interplay of metabolome and gut microbiome in individuals with major depressive disorder vs control individuals