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These side effects are usually mild and tend to improve over time
The two medications work through entirely different mechanisms and are metabolised via separate pathways in the body
Additionally, weight loss can lead to postural changes and altered biomechanics, which may contribute to musculoskeletal discomfort
In Phase 1 detoxification, liver enzymes (primarily the cytochrome P450 family) process these toxins, often making them even more reactive and dangerous in the short term
[8] Hypoglycemia can occur, particularly when tirzepatide is used in combination with insulin or sulfonylureas, though it is uncommon when used as monotherapy due to the glucose-dependent mechanism of insulin secretion
doi: 10.3389/fimmu.2014.00386 188 McCordJ
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