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While present at low abundance in the normal gut, it often exhibits abnormal proliferation during inflammatory states and is considered a prototypical representative of the inflammation-associated microbiota 136

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(2025) Although there is extensive evidence that mechanisms of APAP hepatotoxicity translate to human overdose patients, the vast majority of experiments are performed in young and healthy male mice, which does not reflect the entire spectrum of patients in terms of age, sex, pre-existing conditions, consumption of multiple drugs, etc