For example, in alveolar macrophages, GLP-1 receptor agonism suppressed activation of the NLRP3 inflammasome and reduced production of IL-1 [65], an effect in part mediated by the disruption of histone lactylation, a recognised regulator of pro-fibrotic gene expression [65]
However, this is a theoretical conclusion, and no scientific evidence exists to back this claim
Nevertheless, if advised by a medical professional, evening usage could be appropriate in certain situations
A mild steroid may be added for short periods if inflammation is marked
(2012) 2012:CD007280
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