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Efforts to address and manage GI side effects in the use of oral semaglutide, whether through patient education, proactive symptom management, or considering alternative strategies, are essential in promoting better patient tolerance and adherence to the prescribed medication regimen
Large trials like SELECT, STEP, and PIONEER 7 suggest that with proper medical oversight, semaglutide can be used safely over months or even years
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Semaglutide has a long half-life of about one week
Pregnancy and breastfeeding GLP-1 medications should be discontinued before attempting pregnancy