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Exendin-4 induces bone marrow stromal cells migration through bone marrow-Derived macrophages polarization via PKA-STAT3 signaling pathway

The release of inflammatory mediators leads to increased vascular permeability, contributing to inner ear edema and potential disruption of cochlear ion homeostasis

Perkovic V, Heerspink HL, Chalmers J, Woodward M, Jun M, Li Q, MacMahon S, Cooper ME, Hamet P, Marre M, Mogensen CE, Poulter N, Mancia G, Cass A, Patel A, Zoungas S, ADVANCE Collaborative Group

Take a 48-week break between GLOW cycles

The first action of GLP-1 to be characterised was the stimulation of insulin and inhibition of glucagon release from the pancreatic islets [27]