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IGF-1 LR3 works like natural IGF-1 binding to the IGF-1 receptor

Gene expression analysis shows it modulates over 4,000 human genes, favoring tissue repair, antioxidant defense, and anti-inflammatory pathways

10.2353/ajpath.2008.070583 Am

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Assessment and Monitoring Initial workup should include a basic metabolic panel (to check glucose and electrolytes), a 12-lead ECG, and vital-sign monitoring

Given BPC-157's apparent pro-angiogenic effects (VEGF upregulation), a theoretical concern about promotion of tumor vascularization exists and has not been ruled out by long-term animal studies