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While this idea is somewhat simplified, its intriguing His hypothesis suggests that the sudden influx of B12 can kickstart repair processes, and if there has been long-standing damage, the rapid onset of these processes might overwhelm the system, causing a temporary worsening of symptoms

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These refer to the activity of activation factors

According to WHO, there is a threshold level below which there is no measurable response

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The highest dose arms demonstrated significantly greater weight loss than liraglutide 3.0 mg administered daily (~10.8% vs ~9.0%)