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Pharmacology of testosterone replacement therapy preparations

This delayed emptying contributes to increased satiety and reduced appetite, which supports weight loss but can also produce gastrointestinal side effects

Multiple signaling pathways are implicated in obesity, offering potential therapeutic targets

Some patients may choose to stay on a lower maintenance dose of GLP-1s long-term

IGF-1R is linked to various cytoplasmic second messenger molecules including the RAS-MAPK and PI3K signalling networks

Rising obesity rates and increased healthcare spending also contribute to higher rates of absenteeism and presenteeism, placing a significant burden on employers