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The most common side effects were mild to moderate gastrointestinal symptoms, such as nausea and vomiting, primarily associated with the first dose and substantially reduced with dose escalation

Reassess before any escalation: A dose increase should follow a protocol need and a review of prior observations

Food and Drug Administration (FDA) does not approve supplements for safety and effectiveness, so we recommend choosing brands that have been tested by a credible third-party for purity, potency and safety

It is an issue that future research needs to address

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CrossRef Association between the skeletal muscle-to-visceral fat area ratio and liver fibrosis risk in patients with non-alcoholic fatty liver disease: a cross-sectional study Jingru Liu, Xitong Jiao, Lu Liu, Anqi Chen, Qixue Kang, Jiayue Guo, Yuxing Wang, Yanmeng Qi, Lili You Frontiers in Public Health .2026;[Epub] CrossRef Drug Development for MASHRelated Compensated Cirrhosis: Past, Present and Future RenQiang Zeng, YiXuan Shao, RuTao Lin, XuTing Shen, QinMei Sun, Xin Xin, Ping Liu, JianGao Fan, YiYang Hu, Qin Feng Liver International .2026;[Epub] CrossRef Mediterranean diet adherence and non-alcoholic fatty liver disease risk in Turkish adults: a casecontrol study Reza Khoshbakht Farshad, Elif Akba, Yasemin Erta ztrk British Journal of Nutrition .2026