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doi: 10.1093/CVR/CVZ323 35 PearsonSKietsirirojeNAjjanRA
Dal Lago A, De Martini D, Flore R, et al
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5 Iron homeostasis and immune regulation in the tumor microenvironment 5.1 Impact of macrophage polarization states on iron metabolism During early tumorigenesis, M1-type tumor-associated macrophages (TAMs) facilitate cellular iron uptake via transferrin receptor 1 (TfR1/CD71), while ferritin (FT) restricts iron efflux, resulting in iron sequestration
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