The scavenging of ROS by MTs is beneficial to the prevention of diabetic hyperglycemia, obesity, and the defense against cardiomyopathy, as depicted in Fig
Despite such a likely connection, only one study to date has assessed differences in markers of oxidative damage in children affected with konzo, where increased levels of 8,12-iso-iPF2-VI isoprostane in affected children was associated with deficits in neurocognition, but not deficits in motor impairment 3
Profile of plasma free amino acids, carnitine and acylcarnitines, and JAK2v617f mutation as potential metabolic markers in children with type 1 diabetic nephropathy
Patients should be counselled that the medication is part of a comprehensive treatment plan that includes lifestyle modification, dietary changes, and regular physical activity
The problem is that glutathione itself cannot be taken orally
Understanding whether these medications directly cause breathing difficulties, recognizing when symptoms require medical attention, and identifying alternative explanations are essential for safe medication use