Ash AS, Velazquez R, Kelley CM, Powers BE, Ginsberg SD, Mufson EJ, et al
In medical settings it is usually diluted in normal saline and infused slowly into a vein, with a typical loading dose of 50 mg per kilogram over two to three minutes followed by maintenance doses every six hours or by continuous infusion
Calms + strengthens the skin barrier against daily stressors
It supports the production and function of white blood cells, which are essential in combating pathogens and strengthening the body's defense against infections
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Together, this evidence suggests that stress-induced BBB dysfunction associated with combat may have allowed pyridostigmine to penetrate the brain and exert central neurotoxic effects that are characteristic of Gulf War Syndrome