When symptoms do occur, they typically fall into two categories: local injection site reactions and systemic manifestations that may suggest reduced medication efficacy
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83 Ide, H
8.3% (95% CI, 9.0% to 7.6%) After adjusting for residual confounding factors, the estimated differences in weight loss between tirzepatide and semaglutide were: 2.0% (95% CI, 2.1% to 1.8%) at 3 months 3.2% (95% CI, 3.5% to 3.0%) at 6 months 5.1% (95% CI, 5.8% to 4.3%) at 12 months These findings underscore the superior weight-loss efficacy of tirzepatide, which is attributed to its dual agonist mechanism targeting both GLP-1 and GIP receptors
Richards, R., Whitman, M., Wren, G., & Campion, P