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What makes AOD-9604 unique is its selective action on fat metabolism without producing the other effects associated with full-length human growth hormone, such as increased blood glucose levels, insulin resistance, or excessive IGF-1 production

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Ancient studies carried out in rodents showed that NPY inhibited the GH axis [210], most likely due to the fact that NPY neurons in the arcuate nucleus connect with periventricular SS neurons [211]

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