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Results High doses of GLP1-based multi-agonists improve metabolic function in murine models of PCOS We explored metabolic, hormonal, and gonadal responses to different GLP1-based multi-agonists in two experimental (mouse) models of PCOS, namely PWA (postweaning androgenization) and PNA (prenatal androgenization)
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Pooled cells in vials were thawed, counted and seeded into wells of six-well plates in RPMI-1640 without phenol red (Gibco, 11835030) supplemented with 10% FBS (Sigma-Aldrich, F7524) at a seeding density of 375,000 cells per well
By targeting GLP-1, GIP, and glucagon pathways simultaneously, it may influence appetite control, energy expenditure, and fat metabolism more effectively than traditional treatments
Semaglutide and tirzepatide are both used in medical weight loss care, but they work in different ways
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