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Compounded drugs are not directly approved by the FDA in the same way as commercial drugs
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Phase 2 clinical trial data published in the New England Journal of Medicine (Jastreboff et al., 2023) demonstrated mean body weight reductions of up to approximately 24% over 48 weeks in adults with obesity a notable finding, though long-term durability data and head-to-head comparisons with other treatments are not yet available
PMC 1550477
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These injections are gaining attention because some users report noticeable weight loss results when they use semaglutide with B12
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