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It signals the brain to reduce appetite, stimulates insulin secretion from the pancreas, suppresses glucagon, and slows gastric emptying
Its also your go-to for building and repairing tissues, and proteins are big players in the GLP-1 game
I just spent the weekend at ObesityWeek, a conference that was unsurprisingly dominated by conversations about Wegovy (and Ozempic and tirzepatide and retatrutide and everything coming after those...)
There is no scientific evidence to suggest that injecting in the abdomen causes more nausea than injecting in the thigh or arm
We see many patients who underwent bariatric surgery years ago and have experienced weight regain
Even with perfect compliance, oral formulations achieve roughly 1% bioavailability compared to injectable versions
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