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Therefore, compounds 27 and 28 exhibited the most significant affinity for PDE1B among all the compounds, designating them as potential candidates for synthesis and preclinical assessment to evaluate their PDE1B inhibition and antipsychotic properties (Al-Nema et al., 2023)
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5-HTP (5-Hydroxytryptophan) Derived from Griffonia simplicifolia seeds, 5-HTP is a precursor to serotonin
1b) 3,12
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