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How GLP-1 Medications Affect Your Body GLP-1 receptor agonists mimic a natural hormone called glucagon-like peptide-1
Results The pathogenesis of CKD in patients with T2D likely involves many contributors besides hyperglycemia, such as hypertension, obesity, insulin resistance and glomerular atherosclerosis, exerting kidney damage through metabolic, fibrotic, inflammatory, and hemodynamic mechanisms
Healthcare providers should carefully evaluate the risk-benefit ratio in these situations, considering the metabolic benefits against theoretical concerns
Dowdle et al., 2014
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Though more research is definitely warranted to look at the mechanisms by which GLP-1 medications may work, I have seen some studies indicating that it may be a reduction in chronic inflammation, said Ali
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