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In parallel, metabolic modulators such as metformin, dapagliflozin, and glucagon-like peptide-1 receptor agonists reprogram ovarian bioenergetics by reshaping substrate utilization, suppressing inflammatory and oxidative signaling, and improving mitochondrial efficiency within the ovary
Supplying Gclc KO mice with a high-fat diet (HFD) rescued the decreased triglyceride levels in the serum (Fig
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The rate of discontinuation due to adverse events varied from 5% to 19%, predominantly due to gastrointestinal side effects [17]
Funding The authors declare that no financial support was received for the research and/or publication of this article