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reported that lower levels of TNF- and IL-8 could be observed after 5 weeks of IF (21)

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If I said some of these things, Id be investigated. To critics like Langer, Asprey points to his track record: Whether or not you have a piece of paper isnt a great indication of whether youll help hundreds of thousands of people. Whether the science is robust or reproducible matters less than whether any given product or strategy delivers results

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Body-weight scaling from rat data (roughly 10 mcg per kg) is often cited but remains speculative for humans

The stress-inducible transcription factor NUPR1 targets lipocalin-2 (LCN2), an iron-transporting protein that, along with FPN1, releases Fe 2+ into the extracellular space to suppress ferroptosis [23]